Heat - detector is an Calcium ion channel - isolated using capsaicin binding
Cold receptor - Menthol binding
David
D. McKemy, Werner M. Neuhausser, David Julius
SUMMARY: The cellular and molecular mechanisms that enable us to sense cold
are not well understood. Insights into this process have come from the use...
CONTEXT:
...52 °C (refs 3-5). Insights into the mechanisms of heat sensation have
come from molecular cloning of the vanilloid receptor (VR1), an excitatory ion
channel on sensory neurons that is activated by temperatures exceeding 43 °C,
and......
Nature416, 52 - 58 (07 Mar 2002) Article