Chromosome Structure

The DNA in the eukaryotic cell is organized into a chromosome.

There is a single strand of DNA running the whole length of the chromosome

Circles and Super Coils

Histones are basic proteins found associated with nucleic acids.

Core histone - DNA complex

The DNA is wound around histones forming beads on a string

Nucleosomes are wound to form Solenoids .

Solenoids are linked to scaffold proteins

Summary From Text 11.5

Location of Scafold Associated Regions or SARS on the map

SARs mapped in Drosophila

Dispersive model for nucleosome distribution at the replication fork.

Chromosoxmes are readily visible during metaphase of Mitosis

They are arranged based on size and centromere location.

Human chromosomes 1 and X

Chromosome Isolation

Chromosome Painting

Chromosome - Detail Structure

The sequence of the DNA in Yeast Centromeres has been determined.

Centromere and spindle fiber microtubule

Chromatids, Centromere, and Spindle Fiber.

Problems near the end. How do we keep from loosing DNA on the lagging strand?

Telomeres. Could telomerase may be Ponce DeLeon's fountain of youth?


Text iGenetics by Peter J. Russell


This web site is provided for instruction in Botany and Zoology 342

by Kenneth G. Wilson,
Professor of Botany
Miami University
wilsonkg@muohio.edu